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Index > Protein center > CD3D(Gene name) > Human
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  • CD3D (Gene name),
  • T-cell surface glycoprotein CD3 delta chain (Protein name ),  CD3D_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CD3D(T3D);
    Protein name:
    T-cell surface glycoprotein CD3 delta chain;
    Alternative:
    T-cell receptor T3 delta chain;
    CD:
    CD3d;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.
    Function:
    The CD3 complex mediates signal transduction.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    171
    Sequence:
    50:
    MEHSTFLSGL | VLATLLSQVS | PFKIPIEELE | DRVFVNCNTS | ITWVEGTVGT | 
    100:
    LLSDITRLDL | GKRILDPRGI | YRCNGTDIYK | DKESTVQVHY | RMCQSCVELD | 
    150:
    PATVAGIIVT | DVIATLLLAL | GVFCFAGHET | GRLSGAADTQ | ALLRNDQVYQ | 
    171:
    PLRDRDDAQY | SHLGGNWARN | K
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    SMR:
    UniGene:
    KEGG:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human T-cell surface glycoprotein CD3 delta chain
    Cat.:
    E15221p
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    Packing:
    96T
    ELISA Kit for Human T-cell surface glycoprotein CD3 delta chain
    Cat.:
    E15221r
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    Packing:
    96T
    ELISA Kit for Human T-cell surface glycoprotein CD3 delta chain
    Cat.:
    E15221b
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    ELISA Kit for Human T-cell surface glycoprotein CD3 delta chain
    Cat.:
    E15221m
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    ELISA Kit for Human T-cell surface glycoprotein CD3 delta chain
    Cat.:
    E15221h
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    Packing:
    96T
    CLIA Kit for Human T-cell surface glycoprotein CD3 delta chain
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    U15221r
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    Packing:
    96T
    CLIA Kit for Human T-cell surface glycoprotein CD3 delta chain
    Cat.:
    U15221m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human T-cell surface glycoprotein CD3 delta chain
    Cat.:
    U15221p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human T-cell surface glycoprotein CD3 delta chain
    Cat.:
    U15221h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human T-cell surface glycoprotein CD3 delta chain
    Cat.:
    U15221b
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    Packing:
    96T
    Polyclonal Antibody for Human T-cell surface glycoprotein CD3 delta chain
    Cat.:
    P15221Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human T-cell surface glycoprotein CD3 delta chain
    Polyclonal Antibody for Human T-cell surface glycoprotein CD3 delta chain
    Cat.:
    P15221Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human T-cell surface glycoprotein CD3 delta chain
    Cat.:
    P15221Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human T-cell surface glycoprotein CD3 delta chain
    Monoclonal Antibody for Human T-cell surface glycoprotein CD3 delta chain
    Monoclonal Antibody for Human T-cell surface glycoprotein CD3 delta chain
    Monoclonal Antibody for Human T-cell surface glycoprotein CD3 delta chain
    Monoclonal Antibody for Human T-cell surface glycoprotein CD3 delta chain
    Monoclonal Antibody for Human T-cell surface glycoprotein CD3 delta chain
    Protein for Human T-cell surface glycoprotein CD3 delta chain
    Protein for Human T-cell surface glycoprotein CD3 delta chain
    Protein for Human T-cell surface glycoprotein CD3 delta chain
    Protein for Human T-cell surface glycoprotein CD3 delta chain
    Protein for Human T-cell surface glycoprotein CD3 delta chain

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Exon/intron organization of the genes coding for the delta chains of the human and murine T-cell receptor/T3 complex."
      van den Elsen P. , Georgopoulos K. , Shepley B.-A. , Orkin S. , Terhorst C.
      Proc. Natl. Acad. Sci. U.S.A.83:2944-2948(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "Isolation of cDNA clones encoding the 20K T3 glycoprotein of human T-cell receptor complex."
      van den Elsen P. , Shepley B.-A. , Borst J. , Coligan J.E. , Markham A.F. , Orkin S. , Terhorst C.
      Nature312:413-418(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "T3 delta pre-mRNA is transcribed from a non-TATA promoter and is alternatively spliced in human T cells."
      Tunnacliffe A. , Sims J.E. , Rabbitts T.H.
      EMBO J.5:1245-1252(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "PCR isolation and cloning of novel splice variant mRNAs from known drug target genes."
      Jin P. , Fu G.K. , Wilson A.D. , Yang J. , Chien D. , Hawkins P.R. , Au-Young J. , Stuve L.L.
      Genomics83:566-571(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Blood.
    7. 7.
      "Dephosphorylation of the human T lymphocyte CD3 antigen."
      Alexander D. , Goris J. , Marais R. , Rothbard J. , Merlevede W. , Crumpton M.J.
      Eur. J. Biochem.181:55-65(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 128-171
    8. 8.
      "Effect of CD3delta deficiency on maturation of alpha/beta and gamma/delta T-cell lineages in severe combined immunodeficiency."
      Dadi H.K. , Simon A.J. , Roifman C.M.
      N. Engl. J. Med.349:1821-1828(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN T(-)B(+)NK(+) SCID
    9. 9.
      "Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry."
      Salomon A.R. , Ficarro S.B. , Brill L.M. , Brinker A. , Phung Q.T. , Ericson C. , Sauer K. , Brock A. , Horn D.M. , Schultz P.G. , Peters E.C.
      Proc. Natl. Acad. Sci. U.S.A.100:443-448(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-149;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry."
      Brill L.M. , Salomon A.R. , Ficarro S.B. , Mukherji M. , Stettler-Gill M. , Peters E.C.
      Anal. Chem.76:2763-2772(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-149;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    11. 11.
      "Severe combined immunodeficiency caused by deficiency in either the delta or the epsilon subunit of CD3."
      de Saint Basile G. , Geissmann F. , Flori E. , Uring-Lambert B. , Soudais C. , Cavazzana-Calvo M. , Durandy A. , Jabado N. , Fischer A. , Le Deist F.
      J. Clin. Invest.114:1512-1517(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN IMD19
    12. 12.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-160;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN IMD19
    14. 14.
      "Crystal structure of a human CD3-epsilon/delta dimer in complex with a UCHT1 single-chain antibody fragment."
      Arnett K.L. , Harrison S.C. , Wiley D.C.
      Proc. Natl. Acad. Sci. U.S.A.101:16268-16273(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 23-100 IN COMPLEX WITH CD3E AND ANTIBODY FRAGMENT;SUBUNIT;DISULFIDE BOND
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